Titanium Dioxide
Medically reviewed by Drugs.com. Last updated on Nov 13, 2023.
Excipient (pharmacologically inactive substance)
What is it?
Titanium dioxide (TiO2) is a naturally occurring mineral used as a bright white pigment for paint, in the food industry as a coloring, in sunscreens and cosmetics, and in other industrial uses. After processing, it is exists as white, powdery solid. Titanium dioxide has excellent ultraviolet (UV) resistant qualities and acts as a UV absorbent.
In the pharmaceutical industry, titanium dioxide is used in most sunscreens to block UVA and UVB rays, similar to zinc oxide. It is also commonly used as pigment for pharmaceutical products such as gelatin capsules, tablet coatings and syrups. In the cosmetics industry, it is used in toothpaste, lipsticks, creams, ointments and powders. It can be used as an opacifier to make pigments opaque.[1]
The FDA has approved the safety of titanium dioxide for use as a colorant in food, drugs and cosmetics, including sunscreens. However, controversy exists as to the safety of titanium dioxide nanoparticles used in the cosmetics industry, for example in sunscreens. Titanium and zinc oxides may be made into the nanoparticle size (0.2-100 nanometers) to reduce the white appearance when applied topically, but retain the UV blocking properties. Recent studies suggest titanium dioxide nanoparticles may be toxic, although further research is needed.[2][3]
List of medications using Titanium Dioxide
- Amoxicillin and Clavulanate Potassium 875 mg / 125 mg
- Amoxicillin Trihydrate 500mg
- Cephalexin 500 mg
- Cephalexin Monohydrate 500 mg
- Cetirizine Hydrochloride 10 mg
- Cyclobenzaprine Hydrochloride 10 mg
- Cyclobenzaprine Hydrochloride 10 mg
- Diclofenac Sodium Delayed Release 75 mg
- Diclofenac Sodium Delayed Release 75 mg
- Escitalopram Oxalate 10 mg (base)
- Famotidine 20 mg
- Hydroxyzine Hydrochloride 25 mg
- Ibuprofen 800 mg
- Methocarbamol 500 mg
- Methocarbamol 750 mg
- Ondansetron Hydrochloride 4 mg
- Sertraline Hydrochloride 50 mg
- Sildenafil Citrate 100 mg
- Tramadol Hydrochloride 50 mg
- Tramadol Hydrochloride 50 mg
References
- Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/article/articleDetail.jsp?id=561047. Accessed 08/19/2011
- Biello D. Do nanoparticles and sunscreens mix? Scientific American (online). August 20, 2007; http://www.scientificamerican.com/article.cfm?id=do-nanoparticles-and-sunscreen-mix. Accessed 9/8/2011
- Ju J, Li T. Distinct biological effects of different nanoparticles commonly used in cosmetics and medicine coatings. Cell Biosci. 2011;1:19
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.